LymphedemaV1, Main, Exploration, bibRecord, 006B47

Does resistance to filarial reinfections become leaky over time?

Identifieur interne : 006B47 ( Main/Exploration ); précédent : 006B46; suivant : 006B48

Does resistance to filarial reinfections become leaky over time?

Auteurs : Hans P. Duerr [Allemagne] ; Wolfgang H. Hoffmann ; Martin Eichner

Source :

Trends in parasitology [ 1471-4922 ] ; 2008.

RBID : pubmed:18571986

Descripteurs français

KwdFr :
- Animaux, Filariose lymphatique (immunologie), Filariose lymphatique (parasitologie), Humains, Onchocercose (immunologie), Onchocercose (parasitologie), Récidive, Vaccins (immunologie).
MESH :
- immunologie : Filariose lymphatique, Onchocercose, Vaccins.
- parasitologie : Filariose lymphatique, Onchocercose.
- Animaux, Humains, Récidive.

English descriptors

KwdEn :
- Animals, Elephantiasis, Filarial (immunology), Elephantiasis, Filarial (parasitology), Humans, Onchocerciasis (immunology), Onchocerciasis (parasitology), Recurrence, Vaccines (immunology).
MESH :
- chemical , immunology : Vaccines.
- immunology : Elephantiasis, Filarial, Onchocerciasis.
- parasitology : Elephantiasis, Filarial, Onchocerciasis.
- Animals, Humans, Recurrence.

Abstract

Strategies for the control of human parasitic diseases such as onchocerciasis and lymphatic filariasis require an understanding of how the parasite successfully infects and persists in humans. Despite the fact that the vast majority of infective larvae are eliminated after infection, this 'protection' is far from being an all-or-nothing response. The hypothesis presented here, which is based on epidemiological observations, suggests that the resistance against filarial parasites includes a time-dependent component, probably caused by an early immune response with short-term memory. Validating this hypothesis requires experimental studies with a longitudinal component. Such experiments would help to clarify whether the infection can be controlled by vaccination strategies at all.

DOI: 10.1016/j.pt.2008.04.005
PubMed: 18571986

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Strategies for the control of human parasitic diseases such as onchocerciasis and lymphatic filariasis require an understanding of how the parasite successfully infects and persists in humans. Despite the fact that the vast majority of infective larvae are eliminated after infection, this 'protection' is far from being an all-or-nothing response. The hypothesis presented here, which is based on epidemiological observations, suggests that the resistance against filarial parasites includes a time-dependent component, probably caused by an early immune response with short-term memory. Validating this hypothesis requires experimental studies with a longitudinal component. Such experiments would help to clarify whether the infection can be controlled by vaccination strategies at all.</div>
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Serveur d'exploration sur le lymphœdème

Does resistance to filarial reinfections become leaky over time?

Does resistance to filarial reinfections become leaky over time?

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur le lymphœdème
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